Comparative Genomics Approaches Accurately Predict Deleterious Variants in Plants
نویسندگان
چکیده
منابع مشابه
Analytical Approaches in Comparative Genomics
Traditional biology has changed dramatically in the past two decades to the degree that advancements in the 21st century will be dominated by research at the convergence of biological, physical, and information sciences. Driven by large scientific endeavors such as the human genome project, it has become very much an information science, closely tied to tools and methods of the mathematical sci...
متن کاملComputational approaches for identifying deleterious nonsynonymous variants from human genomes
Identification of the causal genomic variants that alter human phenotypes, particularly those that lead to diseases, is the central goal of human genetics studies. Genome-wide studies have identified several hundreds of common variants associated with complex human diseases and traits. Despite these successes, most of the common variants only have a small individual contribution to the estimate...
متن کاملGenomics Approaches For Improving Salinity Stress Tolerance in Crop Plants
Salinity is one of the major factors which reduces crop production worldwide. Plant responses to salinity are highly complex and involve a plethora of genes. Due to its multigenicity, it has been difficult to attain a complete understanding of how plants respond to salinity. Genomics has progressed tremendously over the past decade and has played a crucial role towards providing necessary knowl...
متن کاملPOGs/PlantRBP: a resource for comparative genomics in plants
POGs/PlantRBP (http://plantrbp.uoregon.edu/) is a relational database that integrates data from rice, Arabidopsis, and maize by placing the complete Arabidopsis and rice proteomes and available maize sequences into 'putative orthologous groups' (POGs). Annotation efforts will focus on predicted RNA binding proteins (RBPs): i.e. those with known RNA binding domains or otherwise implicated in RNA...
متن کاملGreenPhylDB v2.0: comparative and functional genomics in plants
GreenPhylDB is a database designed for comparative and functional genomics based on complete genomes. Version 2 now contains sixteen full genomes of members of the plantae kingdom, ranging from algae to angiosperms, automatically clustered into gene families. Gene families are manually annotated and then analyzed phylogenetically in order to elucidate orthologous and paralogous relationships. T...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: G3 Genes|Genomes|Genetics
سال: 2018
ISSN: 2160-1836
DOI: 10.1534/g3.118.200563